Enhancer of zeste homolog 2 (EZH2)

Definition:

Enhancer of zeste homolog 2 (EZH2) is enzymatic catalytic subunit of Polycomb repressivecomplex 2 (PRC2) that can alter downstream target genes expression by trimethylation of Lys-27 in histone 3 (H3K27me3). EZH2 could also regulate gene expression in ways besides H3K27me3.

References:

[1]. Duan R, et al. EZH2: a novel target for cancer treatment. J Hematol Oncol. 2020 Jul 28;13(1):104. [Content Brief]

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