Fluorescence in situ hybridization (FISH)

Definition:

Fluorescence in situ hybridization (FISH) is a macromolecule recognition technology. FISH uses DNA fragments incorporated with fluorophore-coupled nucleotides as probes, and examine the presence or absence of complementary sequences in fixed cells or tissues under a fluorescent microscope.

References:

[1]. Cui C, et al. Fluorescence In situ Hybridization: Cell-Based Genetic Diagnostic and Research Applications. Front Cell Dev Biol. 2016 Sep 5;4:89. [Content Brief]

Biomedical Dictionary

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