Guanine deaminase

Definition:

Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

References:

[1]. G Yuan, et al. Cloning and characterization of human guanine deaminase. Purification and partial amino acid sequence of the mouse protein. J Biol Chem. 1999 Mar 19;274(12):8175-80. [Content Brief]

[2]. Louise Egeblad, et al. Pan-pathway based interaction profiling of FDA-approved nucleoside and nucleobase analogs with enzymes of the human nucleotide metabolism. PLoS One. 2012;7(5):e37724. [Content Brief]

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