Homeobox protein Hox-D13

Definition:

Sequence-specific transcription factor that binds gene promoters and activates their transcription. Part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis (By similarity).

References:

[1]. Limeng Dai, et al. Mutations in the homeodomain of HOXD13 cause syndactyly type 1-c in two Chinese families. PLoS One. 2014 May 1;9(5):e96192. [Content Brief]

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