Kinesin light chain 2

Definition:

Kinesin is a microtubule-associated force-producing protein that plays a role in organelle transport. The light chain functions in coupling of cargo to the heavy chain or in the modulation of its ATPase activity (Probable). Through binding with PLEKHM2 and ARL8B, recruits kinesin-1 to lysosomes and hence direct lysosomes movement toward microtubule plus ends.

References:

[1]. Cláudia Rosa-Ferreira, et al. Arl8 and SKIP act together to link lysosomes to kinesin-1. Dev Cell. 2011 Dec 13;21(6):1171-8. [Content Brief]

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