P2 receptor family

Definition:

P2 receptor is divided into two major classes, P2X receptors and P2Y receptors (P2YRs). The P2X receptors belong to the ligand-gated cation channel family; whereas the P2Y receptors are members of the seven transmembrane G-protein coupled receptors (GPCRs) family.

References:

[1]. B B Fredholm, et al. Towards a revised nomenclature for P1 and P2 receptors. Trends Pharmacol Sci. 1997 Mar;18(3):79-82. [Content Brief]

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