Parathyroid hormone receptor 1 (PTHR1)

Definition:

Parathyroid hormone receptor 1 (PTHR1) is a family B G-protein-coupled receptor (GPCR) that regulates skeletal development, bone turnover and mineral ion homeostasis. PTHR1 is expressed primarily in bone, kidney and cartilage.

References:

[1]. Cheloha RW, et al. PTH receptor-1 signalling-mechanistic insights and therapeutic prospects. Nat Rev Endocrinol. 2015 Dec;11(12):712-24. [Content Brief]

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