Plasminogen receptor

Definition:

Receptor for plasminogen. Regulates urokinase plasminogen activator-dependent and stimulates tissue-type plasminogen activator-dependent cell surface plasminogen activation. Proposed to be part of a local catecholaminergic cell plasminogen activation system that regulates neuroendocrine prohormone processing. Involved in regulation of inflammatory response; regulates monocyte chemotactic migration and matrix metalloproteinase activation, such as of MMP2 and MMP9.

References:

[1]. Shahrzad Lighvani, et al. Regulation of macrophage migration by a novel plasminogen receptor Plg-R KT. Blood. 2011 Nov 17;118(20):5622-30. [Content Brief]

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