Polymyxin B (PMB)

Definition:

Polymyxin B (PMB) is a decapeptide antibiotic characterized by a heptapeptide ring containing four 2,4-diaminobutyric acids. PMB is bactericidal to almost all gram-negative bacteria at rather low concentrations.

References:

[1]. R Daugelavicius, et al. Stages of polymyxin B interaction with the Escherichia coli cell envelope. Antimicrob Agents Chemother. 2000 Nov;44(11):2969-78. [Content Brief]

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