Proapoptotic nucleolar protein 1

Definition:

Apoptosis-inducing protein that modulates the tumor suppressor function of CDKN2A/p14ARF. Enhances the stability of CDKN2A/p14ARF protein by protecting it from degradation. May act as a tumor suppressor.

References:

[1]. Akihiro Watari, et al. A novel proapoptotic gene PANO encodes a post-translational modulator of the tumor suppressor p14ARF. Exp Cell Res. 2012 Feb 1;318(3):187-95. [Content Brief]

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