Progerin

Definition:

Progerin, a truncated unprocessed lamin A protein, causes tissue aging and degeneration. Progerin can be used for the research of premature aging disorder including Hutchinson-Gilford progeria syndrome (HGPS).

References:

[1]. Xiaolong Xu, et al. Progerin accumulation in nucleus pulposus cells impairs mitochondrial function and induces intervertebral disc degeneration and therapeutic effects of sulforaphane. Theranostics. 2019 Apr 12;9(8):2252-2267. [Content Brief]

Biomedical Dictionary

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