Protein transport protein Sec16B

Definition:

Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. Involved in peroxisome biogenesis. Regulates the transport of peroxisomal biogenesis factors PEX3 and PEX16 from the ER to peroxisomes.

References:

[1]. Annika Budnik, et al. Characterization of human Sec16B: indications of specialized, non-redundant functions. Sci Rep. 2011;1:77. [Content Brief]

[2]. Dibyendu Bhattacharyya, et al. Two mammalian Sec16 homologues have nonredundant functions in endoplasmic reticulum (ER) export and transitional ER organization. Mol Biol Cell. 2007 Mar;18(3):839-49. [Content Brief]

[3]. Shusuke Yonekawa, et al. Sec16B is involved in the endoplasmic reticulum export of the peroxisomal membrane biogenesis factor peroxin 16 (Pex16) in mammalian cells. Proc Natl Acad Sci U S A. 2011 Aug 2;108(31):12746-51. [Content Brief]

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