Protein tyrosine phosphatases (PTPs)

Definition:

Protein tyrosine phosphatases (PTPs) are a family of enzymes that catalyze the dephosphorylation of tyrosine (Tyr)-phosphorylated proteins. PTPs modulate the cellular level of tyrosine phosphorylation under normal and pathological conditions, and thus exert either stimulatory or inhibitory effect on signal transduction.

References:

[1]. Kuban-Jankowska A, et al. Protein tyrosine phosphatases in pathological process. Front Biosci (Landmark Ed). 2015 Jan 1;20(2):377-88. [Content Brief]

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