Radial spoke head protein 9 homolog

Definition:

Component of the axonemal radial spoke head which plays an important role in ciliary motility. Essential for both the radial spoke head assembly and the central pair microtubule stability in ependymal motile cilia (By similarity). Required for motility of olfactory and neural cilia and for the structural integrity of ciliary axonemes in both 9+0 and 9+2 motile cilia (By similarity).

References:

[1]. Victoria H Castleman, et al. Mutations in radial spoke head protein genes RSPH9 and RSPH4A cause primary ciliary dyskinesia with central-microtubular-pair abnormalities. Am J Hum Genet. 2009 Feb;84(2):197-209. [Content Brief]

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