Ras-related and estrogen-regulated growth inhibitor

Definition:

Binds GDP/GTP and possesses intrinsic GTPase activity. Has higher affinity for GDP than for GTP. In cell lines overexpression leads to a reduction in the rate of proliferation, colony formation and in tumorigenic potential.

References:

[1]. B S Finlin, et al. RERG is a novel ras-related, estrogen-regulated and growth-inhibitory gene in breast cancer. J Biol Chem. 2001 Nov 9;276(45):42259-67. [Content Brief]

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