Scrub typhus

Definition:

Scrub typhus, also known as tsutsugamushi disease, is a zoonosis caused by Orientia tsutsugamushi, an obligate intracellular bacterium that is transmitted by the Leptotrombidium species mite. The disease is confined to East Asia and characterized by fever, rash, eschar, pneumonitis, meningitis, and disseminated intravascular coagulation.

References:

[1]. S Y Seong, et al. Orientia tsutsugamushi infection: overview and immune responses. Microbes Infect. 2001 Jan;3(1):11-21. [Content Brief]

[2]. Yan Ge, et al. Subversion of host cell signaling by Orientia tsutsugamushi. Microbes Infect. 2011 Jul;13(7):638-48. [Content Brief]

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