Sterol regulatory element-binding protein 2 (SREBP2)

Definition:

Sterol regulatory element-binding protein 2 (SREBP2) is a transcription factor which controls cholesterol homeostasis by regulating transcription of sterol-regulated genes.

References:

[1]. Fowler JWM, et al. Inflammatory stress signaling via NF-kB alters accessible cholesterol to upregulate SREBP2 transcriptional activity in endothelial cells. Elife. 2022 Aug 12;11:e79529. [Content Brief]

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