T-complex protein 1 subunit eta

Definition:

Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. The TRiC complex plays a role in the folding of actin and tubulin (Probable).

References:

[1]. Adam Freund, et al. Proteostatic control of telomerase function through TRiC-mediated folding of TCAB1. Cell. 2014 Dec 4;159(6):1389-403. [Content Brief]

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