The tuberous sclerosis complex 1/2 (TSC1/2)

Definition:

The tuberous sclerosis complex 1/2 (TSC1/2) is a negative regulator of the nutrient-sensing kinase mechanistic target of rapamycin complex (mTORC1), and its function is generally associated with tumor suppression.

References:

[1]. Götz Hartleben, et al. Tuberous sclerosis complex is required for tumor maintenance in MYC-driven Burkitt's lymphoma. EMBO J. 2018 Nov 2;37(21):e98589. [Content Brief]

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