Xaa-Pro aminopeptidase 2

Definition:

Membrane-bound metalloprotease which catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides, such as Arg-Pro-Pro. May play a role in the metabolism of the vasodilator bradykinin.

References:

[1]. Giuseppe Molinaro, et al. Human recombinant membrane-bound aminopeptidase P: production of a soluble form and characterization using novel, internally quenched fluorescent substrates. Biochem J. 2005 Jan 15;385(Pt 2):389-97. [Content Brief]

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