2. PROTAC
  3. PROTAC Linkers
  4. Biotin-bis-amido-SS-NHS

Biotin-bis-amido-SS-NHS is an Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs.

For research use only. We do not sell to patients.

Biotin-bis-amido-SS-NHS Chemical Structure

Biotin-bis-amido-SS-NHS Chemical Structure

CAS No. : 142439-92-7

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100 mg USD 450 Get quote 6 - 7 weeks 6 - 7 weeks 5 - 6 weeks
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Based on 1 publication(s) in Google Scholar

Biotin-bis-amido-SS-NHS Related Antibodies

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Description

Biotin-bis-amido-SS-NHS is an Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs.

IC50 & Target[1]

Alkyl/ether

 

In Vitro

Biotin-bis-amido-SS-NHS is a long arm biotin containing disulfide bond, and the compound can be applied to biochemistry detection field, reduce the influence of steric effect, improve the sensitivity of detection[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.
PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Biotin-bis-amido-SS-NHS Related Antibodies
Molecular Weight

575.72

Formula

C22H33N5O7S3
CAS No.
SMILES

O=C(NCCNC(CCSSCCC(ON1C(CCC1=O)=O)=O)=O)CCCC[C@@H]2SC[C@]([C@]2([H])N3)([H])NC3=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Biotin-bis-amido-SS-NHS Related Classifications

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  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Biotin-bis-amido-SS-NHS142439-92-7PROTAC LinkersProtaclinkercancerPEGbiotinInhibitorinhibitorinhibit

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