Biotin-C1-PEG3-C3-amido-C5-Gly-Arg-Gly-N3 TFA

Cat. No.: HY-131455A Purity: ≥98.0%: FAQs
Data Sheet SDS COA Handling Instructions

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Biotin-C1-PEG3-C3-amido-C5-Gly-Arg-Gly-N3 TFA is used for detection of modification site for N-myristoylated and GPI-anchored proteins in blood-stage P. falciparum. Biotin-C1-PEG3-C3-amido-C5-Gly-Arg-Gly-N3 (TFA) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

For research use only. We do not sell to patients.

Biotin-C1-PEG3-C3-amido-C5-Gly-Arg-Gly-N3 TFA Chemical Structure

Size	Price	Stock	Quantity
5 mg	USD 600	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 950	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 1850	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Biotin-C1-PEG3-C3-amido-C5-Gly-Arg-Gly-N3 TFA is used for detection of modification site for N-myristoylated and GPI-anchored proteins in blood-stage P. falciparum^[1]. Biotin-C1-PEG3-C3-amido-C5-Gly-Arg-Gly-N3 (TFA) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Molecular Weight

970.07

Formula

C₃₈H₆₆F₃N₁₃O₁₁S

Appearance

Solid

Color

White to off-white

SMILES

[N-]=[N+]=NCC(N[C@@H](CCCNC(N)=N)C(NCC(NCCCCCC(NCCCOCCOCCOCCCNC(CCCC[C@H]1[C@]2([H])[C@](NC(N2)=O)([H])CS1)=O)=O)=O)=O)=O.OC(C(F)(F)F)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (103.09 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.0309 mL	5.1543 mL	10.3085 mL
5 mM	0.2062 mL	1.0309 mL	2.0617 mL
10 mM	0.1031 mL	0.5154 mL	1.0309 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

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Dosage

mg/kg

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μL

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: ≥98.0%

Select Batch:

Data Sheet (274 KB) SDS (252 KB)

COA (254 KB) HNMR (203 KB) MS (70 KB)

Handling Instructions (2659 KB)

References

[1]. Malgorzata Broncel, et al. Multifunctional reagents for quantitative proteome-wide analysis of protein modification in human cells and dynamic profiling of protein lipidation during vertebrate development. Angew Chem Int Ed Engl. 2015 May 11;54(20):5948-51. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.0309 mL	5.1543 mL	10.3085 mL	25.7713 mL
	5 mM	0.2062 mL	1.0309 mL	2.0617 mL	5.1543 mL
	10 mM	0.1031 mL	0.5154 mL	1.0309 mL	2.5771 mL
	15 mM	0.0687 mL	0.3436 mL	0.6872 mL	1.7181 mL
	20 mM	0.0515 mL	0.2577 mL	0.5154 mL	1.2886 mL
	25 mM	0.0412 mL	0.2062 mL	0.4123 mL	1.0309 mL
	30 mM	0.0344 mL	0.1718 mL	0.3436 mL	0.8590 mL
	40 mM	0.0258 mL	0.1289 mL	0.2577 mL	0.6443 mL
	50 mM	0.0206 mL	0.1031 mL	0.2062 mL	0.5154 mL
	60 mM	0.0172 mL	0.0859 mL	0.1718 mL	0.4295 mL
	80 mM	0.0129 mL	0.0644 mL	0.1289 mL	0.3221 mL
	100 mM	0.0103 mL	0.0515 mL	0.1031 mL	0.2577 mL