2. Peptides
  3. Peptide and Derivatives
  4. Inhibitors and Substrates
  5. Biotin-H10

Biotin-H10 is a specific anterior gradient homolog 2 (AGR2) inhibitor with a KD of 6.4 nM. Biotin-H10 inhibits cancer cells viability.

For research use only. We do not sell to patients.

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Biotin-H10 Chemical Structure

Biotin-H10 Chemical Structure

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1 mg USD 60 In-stock
5 mg USD 190 In-stock
10 mg USD 305 In-stock
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Based on 1 publication(s) in Google Scholar

Biotin-H10 Related Antibodies

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Description

Biotin-H10 is a specific anterior gradient homolog 2 (AGR2) inhibitor with a KD of 6.4 nM. Biotin-H10 inhibits cancer cells viability[1].

IC50 & Target

KD: 6.4 nM (AGR2)[1]
Molecular Weight

1822.22

Formula

C79H132N22O21S3
Appearance

Solid

Color

White to off-white

Sequence

{Biotin}-Gly-Gly-Gly-Ser-Gly-Met-Lys-Met-Gln-Val-Arg-Ile-Tyr-Leu-Val
Sequence Shortening

{Biotin}-GGGSGMKMQVRIYLV
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture and light

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (27.44 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.5488 mL 2.7439 mL 5.4878 mL
5 mM 0.1098 mL 0.5488 mL 1.0976 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.5488 mL 2.7439 mL 5.4878 mL 13.7195 mL
5 mM 0.1098 mL 0.5488 mL 1.0976 mL 2.7439 mL
10 mM 0.0549 mL 0.2744 mL 0.5488 mL 1.3720 mL
15 mM 0.0366 mL 0.1829 mL 0.3659 mL 0.9146 mL
20 mM 0.0274 mL 0.1372 mL 0.2744 mL 0.6860 mL
25 mM 0.0220 mL 0.1098 mL 0.2195 mL 0.5488 mL
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Biotin-H10 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Biotin-H10Othersbreast cancerprostate cancerMDA-MB-231PC-3Inhibitorinhibitorinhibit

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