Bis-PEG3-NHS ester

Cat. No.: HY-130087 Purity: ≥97.0%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Bis-PEG3-NHS ester is a nonclaevable 3-unit PEG linker for antibody-agent-conjugation (ADC).

For research use only. We do not sell to patients.

Bis-PEG3-NHS ester Chemical Structure

CAS No. : 1314378-16-9

Size	Price	Stock	Quantity
50 mg	USD 63	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 100	In-stock	Estimated Time of Arrival: December 31
250 mg	USD 150	In-stock	Estimated Time of Arrival: December 31
500 mg		Get quote
1 g		Get quote

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Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
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Description

Bis-PEG3-NHS ester is a nonclaevable 3-unit PEG linker for antibody-agent-conjugation (ADC).

IC₅₀ & Target

Non-cleavable Linker

Molecular Weight

444.39

Formula

C₁₈H₂₄N₂O₁₁

CAS No.

1314378-16-9

Appearance

Solid

Color

White to off-white

SMILES

O=C(ON1C(CCC1=O)=O)CCOCCOCCOCCC(ON2C(CCC2=O)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (225.03 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.2503 mL	11.2514 mL	22.5028 mL
5 mM	0.4501 mL	2.2503 mL	4.5006 mL
10 mM	0.2250 mL	1.1251 mL	2.2503 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

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Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: ≥97.0%

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Data Sheet (240 KB) SDS (252 KB)

COA (244 KB) HNMR (127 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.2503 mL	11.2514 mL	22.5028 mL	56.2569 mL
	5 mM	0.4501 mL	2.2503 mL	4.5006 mL	11.2514 mL
	10 mM	0.2250 mL	1.1251 mL	2.2503 mL	5.6257 mL
	15 mM	0.1500 mL	0.7501 mL	1.5002 mL	3.7505 mL
	20 mM	0.1125 mL	0.5626 mL	1.1251 mL	2.8128 mL
	25 mM	0.0900 mL	0.4501 mL	0.9001 mL	2.2503 mL
	30 mM	0.0750 mL	0.3750 mL	0.7501 mL	1.8752 mL
	40 mM	0.0563 mL	0.2813 mL	0.5626 mL	1.4064 mL
	50 mM	0.0450 mL	0.2250 mL	0.4501 mL	1.1251 mL
	60 mM	0.0375 mL	0.1875 mL	0.3750 mL	0.9376 mL
	80 mM	0.0281 mL	0.1406 mL	0.2813 mL	0.7032 mL
	100 mM	0.0225 mL	0.1125 mL	0.2250 mL	0.5626 mL