2. Membrane Transporter/Ion Channel
  3. Sodium Channel
  4. BmK-M1

BmK-M1 is a scorpion toxin, and is composed of 64 amino acids cross-linked by four disulfide bridges. BmK-M1 inhibits Na+ channel and can be considered both as a cardiotoxin and a neurotoxin.

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BmK-M1 Chemical Structure

BmK-M1 Chemical Structure

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BmK-M1 Related Antibodies

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Description

BmK-M1 is a scorpion toxin, and is composed of 64 amino acids cross-linked by four disulfide bridges. BmK-M1 inhibits Na+ channel and can be considered both as a cardiotoxin and a neurotoxin[1].

Molecular Weight

7217.13

Formula

C313H467N91O91S8
Sequence

Val-Arg-Asp-Ala-Tyr-Ile-Ala-Lys-Pro-His-Asn-Cys-Val-Tyr-Glu-Cys-Ala-Arg-Asn-Glu-Tyr-Cys-Asn-Asp-Leu-Cys-Thr-Lys-Asn-Gly-Ala-Lys-Ser-Gly-Tyr-Cys-Gln-Trp-Val-Gly-Lys-Tyr-Gly-Asn-Gly-Cys-Trp-Cys-Ile-Glu-Leu-Pro-Asp-Asn-Val-Pro-Ile-Arg-Val-Pro-Gly-Lys-Cys-His (Disulfide bridge:Cys12-Cys63;Cys16-Cys36;Cys22-Cys46;Cys26-Cys48)
Sequence Shortening

VRDAYIAKPHNCVYECARNEYCNDLCTKNGAKSGYCQWVGKYGNGCWCIELPDNVPIRVPGKCH (Disulfide bridge:Cys12-Cys63;Cys16-Cys36;Cys22-Cys46;Cys26-Cys48)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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BmK-M1 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BmK-M1Sodium ChannelNa channelsNa+ channelscardiotoxinneurotoxinscorpion toxinNa+ channelInhibitorinhibitorinhibit

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