2. TGF-beta/Smad
  3. TGF-β Receptor
  4. BMPR2-IN-1

BMPR2-IN-1 (Compound 8a) is a BMPR2 inhibitor with an IC50 of 506 nM and a KD of 83.5 nM. BMPR2-IN-1 can be used for research of pulmonary arterial hypertension, Alzheimer’s disease and cancer.

For research use only. We do not sell to patients.

BMPR2-IN-1 Chemical Structure

BMPR2-IN-1 Chemical Structure

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Other Forms of BMPR2-IN-1:

BMPR2-IN-1 Related Antibodies

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Description

BMPR2-IN-1 (Compound 8a) is a BMPR2 inhibitor with an IC50 of 506 nM and a KD of 83.5 nM. BMPR2-IN-1 can be used for research of pulmonary arterial hypertension, Alzheimer’s disease and cancer[1].

Molecular Weight

321.34

Formula

C16H15N7O
SMILES

O=C1NCCC2=CC=C(NC3=NC(NC4=NNC1=C4)=CC=N3)C=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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BMPR2-IN-1 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BMPR2-IN-1TGF-β ReceptorTransforming growth factor beta receptorsPulmonary arterial hypertensionAlzheimer’s diseasecancerInhibitorinhibitorinhibit

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