2. GPCR/G Protein
  3. Endothelin Receptor
  4. BMS-193884

BMS-193884 is a selective, orally active, and competitive ETA antagonist with 10000-fold greater affinity for the human ETA receptor (Ki=1.4 nM) than for the ETB receptor.

For research use only. We do not sell to patients.

BMS-193884 Chemical Structure

BMS-193884 Chemical Structure

CAS No. : 176960-47-7

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BMS-193884 Related Antibodies

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Description

BMS-193884 is a selective, orally active, and competitive ETA antagonist with 10000-fold greater affinity for the human ETA receptor (Ki=1.4 nM) than for the ETB receptor[1].

IC50 & Target[1]

ETA

1.4 nM (Ki)

ETB

18700 nM (Ki)

Molecular Weight

395.43

Formula

C20H17N3O4S
CAS No.
SMILES

O=S(C1=CC=CC=C1C2=CC=C(C3=NC=CO3)C=C2)(NC4=C(C)C(C)=NO4)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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BMS-193884 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BMS-193884176960-47-7BMS193884BMS 193884Endothelin Receptororalendothelinselectivecongestive heart failurepulmonary hypertensionInhibitorinhibitorinhibit

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HY-19263
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