BnO-PEG5-OH

Cat. No.: HY-W042714: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

BnO-PEG5-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

For research use only. We do not sell to patients.

BnO-PEG5-OH Chemical Structure

CAS No. : 57671-28-0

Size	Price	Stock
1 g	USD 35	Ask For Quote & Lead Time
5 g	USD 73	Ask For Quote & Lead Time
10 g	USD 125	Ask For Quote & Lead Time
25 g	USD 250	Ask For Quote & Lead Time

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Biological Activity
Purity & Documentation
References
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Description

BnO-PEG5-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

IC₅₀ & Target

PEGs

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

328.40

Formula

C₁₇H₂₈O₆

CAS No.

57671-28-0

Appearance

Liquid (Density: 1.10 g/cm³)

Color

Colorless to light yellow

SMILES

OCCOCCOCCOCCOCCOCC1=CC=CC=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Pure form	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Purity & Documentation

Purity: 98.55%

Select Batch:

Data Sheet (262 KB) SDS (251 KB)

COA (239 KB) HNMR (116 KB) RP-HPLC (245 KB)

Handling Instructions (2659 KB)

References

[1]. Girardini M, et al. Cereblon versus VHL: Hijacking E3 ligases against each other using PROTACs. Bioorg Med Chem. 2019 Jun 15;27(12):2466-2479. [Content Brief]

BnO-PEG5-OH Related Classifications

Molarity Calculator
Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BnO-PEG5-OH57671-28-0PROTAC LinkersInhibitorinhibitorinhibit

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