2. Membrane Transporter/Ion Channel
  3. ATP Synthase
  4. Bongkrekic acid

Bongkrekic acid is a mitochondrial toxin secreted by the bacteria Pseudomonas cocovenenans. Bongkrekic acid specific ligand for mitochondrial adenine nucleotide translocase (ANT) rather than the electron transport chain. Bongkrekic acid has to cross the mitochondrial inner membrane to produce its inhibitory effect on ADP/ATP transport.

For research use only. We do not sell to patients.

Bongkrekic acid Chemical Structure

Bongkrekic acid Chemical Structure

CAS No. : 11076-19-0

Size Price Stock Quantity
Solvent
100 μg（2.06 mM in 100 μL Tris） USD 350 In-stock
Solvent
500 μg（2.06 mM in 500 μL Tris） USD 998 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Bongkrekic acid:

Bongkrekic acid Related Antibodies

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Description

Bongkrekic acid is a mitochondrial toxin secreted by the bacteria Pseudomonas cocovenenans[1]. Bongkrekic acid specific ligand for mitochondrial adenine nucleotide translocase (ANT) rather than the electron transport chain. Bongkrekic acid has to cross the mitochondrial inner membrane to produce its inhibitory effect on ADP/ATP transport[2].

In Vitro

Bongkrekic acid (0-50 μM; 48 hours) stimulated formazan formation in MDA-MB-231, MCF-7 and LTED cells with EC50 of 34.14 μM, >50 μM and 2.58 μM, respectively.
Bongkrekic acid (0.1-25 μM; 48 hours) decreases the living cell numbers in LTED cells and parent MCF-7 cells in a dose-dependent manner[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Bongkrekic acid Related Antibodies
Molecular Weight

486.60

Formula

C28H38O7
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

OC(CC(/C=C/[C@@H](C)C/C=C/CC/C=C/C=C\C[C@@H](OC)/C(C)=C\C=C(C)\C(O)=O)=C/C(O)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Solution, -20°C, 2 years
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (205.51 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

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Purity & Documentation

Purity: ≥99.0%

SDS (393 KB)

COA (242 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.0551 mL 10.2754 mL 20.5508 mL 51.3769 mL
5 mM 0.4110 mL 2.0551 mL 4.1102 mL 10.2754 mL
10 mM 0.2055 mL 1.0275 mL 2.0551 mL 5.1377 mL
15 mM 0.1370 mL 0.6850 mL 1.3701 mL 3.4251 mL
20 mM 0.1028 mL 0.5138 mL 1.0275 mL 2.5688 mL
25 mM 0.0822 mL 0.4110 mL 0.8220 mL 2.0551 mL
30 mM 0.0685 mL 0.3425 mL 0.6850 mL 1.7126 mL
40 mM 0.0514 mL 0.2569 mL 0.5138 mL 1.2844 mL
50 mM 0.0411 mL 0.2055 mL 0.4110 mL 1.0275 mL
60 mM 0.0343 mL 0.1713 mL 0.3425 mL 0.8563 mL
80 mM 0.0257 mL 0.1284 mL 0.2569 mL 0.6422 mL
100 mM 0.0206 mL 0.1028 mL 0.2055 mL 0.5138 mL
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Bongkrekic acid Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Bongkrekic acid11076-19-0ATP SynthaseInhibitorinhibitorinhibit

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