Bortezomib (Standard)

Cat. No.: HY-10227R Purity: ≥98%: FAQs
Handling Instructions

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Bortezomib (Standard) is the analytical standard of Bortezomib. This product is intended for research and analytical applications. Bortezomib (PS-341) is a reversible and selective proteasome inhibitor, and potently inhibits 20S proteasome (K_i=0.6 nM) by targeting a threonine residue. Bortezomib disrupts the cell cycle, induces apoptosis, and inhibits NF-κB. Bortezomib is the first proteasome inhibitor anticancer agent. Anti-cancer activity.

For research use only. We do not sell to patients.

Bortezomib (Standard) Chemical Structure

CAS No. : 179324-69-7

Size	Price	Stock
5 mg	USD 160	Ask For Quote & Lead Time
10 mg	USD 240	Ask For Quote & Lead Time
25 mg	USD 380	Ask For Quote & Lead Time
50 mg	USD 494	Ask For Quote & Lead Time
100 mg	USD 643	Ask For Quote & Lead Time

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This product is a controlled substance and not for sale in your territory.

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Description	Bortezomib (Standard) is the analytical standard of Bortezomib . This product is intended for research and analytical applications. Bortezomib (PS-341) is a reversible and selective proteasome inhibitor, and potently inhibits 20S proteasome (K_i=0.6 nM) by targeting a threonine residue. Bortezomib disrupts the cell cycle, induces apoptosis, and inhibits NF-κB. Bortezomib is the first proteasome inhibitor anticancer agent. Anti-cancer activity.
Molecular Weight	384.24
Formula	C₁₉H₂₅BN₄O₄
CAS No.	179324-69-7
SMILES	OB(O)[C@H](CC(C)C)NC([C@@H](NC(C1=NC=CN=C1)=O)CC2=CC=CC=C2)=O
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Handling Instructions (2659 KB)

Bortezomib (Standard) Related Classifications

Molarity Calculator
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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Bortezomib (Standard)179324-69-7ProteasomeNF-κBApoptosisAutophagyNuclear factor-κBNuclear factor-kappaBInhibitorinhibitorinhibit

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Bortezomib (Standard)

Product Information

Purity & Documentation

Customer Review