2. PROTAC
  3. Target Protein Ligand-Linker Conjugates
  4. BRD4 ligand-Linker Conjugate 1 TFA

BRD4 ligand-Linker Conjugate 1 TFA 

Cat. No.: HY-132943A Purity: 98.66%
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BRD4 ligand-Linker Conjugate 1 TFA (compound 106-1) is a target protein ligand-linker conjugate that can be used in the synthesis of PROTACs.

For research use only. We do not sell to patients.

BRD4 ligand-Linker Conjugate 1 TFA Chemical Structure

BRD4 ligand-Linker Conjugate 1 TFA Chemical Structure

Size Price Stock Quantity
5 mg USD 750 In-stock
10 mg USD 1200 In-stock
25 mg USD 2400 In-stock
50 mg USD 3850 In-stock
100 mg USD 6200 In-stock
200 mg   Get quote  
500 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

Other Forms of BRD4 ligand-Linker Conjugate 1 TFA:

BRD4 ligand-Linker Conjugate 1 TFA Related Antibodies

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Description

BRD4 ligand-Linker Conjugate 1 TFA (compound 106-1) is a target protein ligand-linker conjugate that can be used in the synthesis of PROTACs[1][2].

Molecular Weight

614.06

Formula

C30H31ClF3N7O2
Appearance

Viscous Liquid

Color

Light yellow to brown

SMILES

ClC1=CC=C(C2=NC3(CC3)C4=NN=C(C)N4C5=CC=C(C6=CN(CCCCCCN)N=C6)C=C25)C=C1.OC(C(F)(F)F)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, stored under nitrogen, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (162.85 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.6285 mL 8.1425 mL 16.2851 mL
5 mM 0.3257 mL 1.6285 mL 3.2570 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 1.6285 mL 8.1425 mL 16.2851 mL 40.7126 mL
5 mM 0.3257 mL 1.6285 mL 3.2570 mL 8.1425 mL
10 mM 0.1629 mL 0.8143 mL 1.6285 mL 4.0713 mL
15 mM 0.1086 mL 0.5428 mL 1.0857 mL 2.7142 mL
20 mM 0.0814 mL 0.4071 mL 0.8143 mL 2.0356 mL
25 mM 0.0651 mL 0.3257 mL 0.6514 mL 1.6285 mL
30 mM 0.0543 mL 0.2714 mL 0.5428 mL 1.3571 mL
40 mM 0.0407 mL 0.2036 mL 0.4071 mL 1.0178 mL
50 mM 0.0326 mL 0.1629 mL 0.3257 mL 0.8143 mL
60 mM 0.0271 mL 0.1357 mL 0.2714 mL 0.6785 mL
80 mM 0.0204 mL 0.1018 mL 0.2036 mL 0.5089 mL
100 mM 0.0163 mL 0.0814 mL 0.1629 mL 0.4071 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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BRD4 ligand-Linker Conjugate 1 TFA Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BRD4 ligand-Linker Conjugate 1Target Protein Ligand-Linker ConjugatesInhibitorinhibitorinhibit

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