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  4. BRD5080

BRD5080 is a potent GPR65 positive allosteric modulator. BRD5080 induces GPR65-dependent cAMP production. BRD5080 exhibits a robust induction of cAMP activity and recruits G protein for the WT and variant hGPR65 as well as for the mouse ortholog. BRD5080 has the potential for autoimmune and inflammatory diseases research.

For research use only. We do not sell to patients.

BRD5080 Chemical Structure

BRD5080 Chemical Structure

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BRD5080 Related Antibodies

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Description

BRD5080 is a potent GPR65 positive allosteric modulator. BRD5080 induces GPR65-dependent cAMP production. BRD5080 exhibits a robust induction of cAMP activity and recruits G protein for the WT and variant hGPR65 as well as for the mouse ortholog. BRD5080 has the potential for autoimmune and inflammatory diseases research[1].

Molecular Weight

434.46

Formula

C24H23FN4O3
SMILES

O=C1C=C(C2=CC=C(COC(C)C)C=C2)NC3=C(C(NC4=C(F)C=C(C)C=C4)=O)C=NN31
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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BRD5080 Related Classifications

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BRD5080BRD 5080BRD-5080OthersGPR65cAMPG proteinautoimmuneinflammatory diseasesInhibitorinhibitorinhibit

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