Brivanib (alaninate) (Standard) (Synonyms: BMS-582664 (Standard))

Cat. No.: HY-10336R Purity: ≥98%: FAQs
Handling Instructions Technical Support

Brivanib (alaninate) (Standard) is the analytical standard of Brivanib (alaninate). This product is intended for research and analytical applications. Brivanib alaninate (BMS-582664) is an ATP-competitive inhibitor against VEGFR2 with an IC50 of 25 nM; has moderate potency against VEGFR-1 and FGFR-1, but more than 240-fold against PDGFRβ[1].

For research use only. We do not sell to patients.

Brivanib (alaninate) (Standard) Chemical Structure

CAS No. : 649735-63-7

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Description	Brivanib (alaninate) (Standard) is the analytical standard of Brivanib (alaninate). This product is intended for research and analytical applications. Brivanib alaninate (BMS-582664) is an ATP-competitive inhibitor against VEGFR2 with an IC50 of 25 nM; has moderate potency against VEGFR-1 and FGFR-1, but more than 240-fold against PDGFRβ[1].
Molecular Weight	441.46
Formula	C₂₂H₂₄FN₅O₄
CAS No.	649735-63-7
SMILES	O=C(O[C@@H](COC1=CN2C(C(OC3=C(C4=C(NC(C)=C4)C=C3)F)=NC=N2)=C1C)C)[C@@H](N)C
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Handling Instructions (2659 KB)

Brivanib (alaninate) (Standard) Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
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The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Brivanib (alaninate) (Standard)649735-63-7BMS-582664 (Standard)VEGFRAutophagyVascular endothelial growth factor receptorInhibitorinhibitorinhibit

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Brivanib (alaninate) (Standard) (Synonyms: BMS-582664 (Standard))

Product Information

Purity & Documentation

Customer Review

Brivanib (alaninate) (Standard) Related Classifications

Molarity Calculator

Dilution Calculator