Bromodiphenhydramine  (Synonyms: Ambodryl)

Bromodiphenhydramine (Ambodryl) is a potent antihistamine with antimicrobial property. Bromodiphenhydramine inhibits a large number of Gram negative and Gram positive bacteria. Bromodiphenhydramine can be used for cutaneous allergies research^[1][2][3].

Bromodiphenhydramine (1.5 and 3 μg/g, single) protects mice against a challenge with a virulent strain of Salmonella typhimurium, and also significantly reduces the multiplication of this organism in the liver, spleen and blood of the protected animals in comparison with the unprotected controls^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

334.25

C₁₇H₂₀BrNO

118-23-0

BrC1=CC=C(C(C2=CC=CC=C2)OCCN(C)C)C=C1

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. MOLINA EB. [A new antihistaminic, bromodiphenhydramine hydrochloride, in the control of cutaneous allergies]. Sem Med. 1960 Jul 11;117:151-2. Spanish.  [Content Brief]

  [2]. Dastidar SG, et al. Antibacterial activity of ambodryl and benadryl. J Appl Bacteriol. 1976 Oct;41(2):209-14.  [Content Brief]

  [3]. Ray S, et al. Studies on synergism between penicillins and ambodryl (bromodiphenhydramine HCl), an antihistamine with antimicrobial property. Indian J Exp Biol. 1990 Mar;28(3):253-8.   [Content Brief]