2. GPCR/G Protein Neuronal Signaling Immunology/Inflammation Anti-infection
  3. Histamine Receptor Bacterial
  4. Bromodiphenhydramine hydrochloride

Bromodiphenhydramine hydrochloride  (Synonyms: Ambodryl hydrochloride)

Cat. No.: HY-B1568A Purity: 97.34%
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Bromodiphenhydramine hydrochloride is a potent antihistamine with antimicrobial property. Bromodiphenhydramine hydrochloride inhibits a large number of Gram negative and Gram positive bacteria. Bromodiphenhydramine hydrochloride can be used for cutaneous allergies research.

For research use only. We do not sell to patients.

Bromodiphenhydramine hydrochloride Chemical Structure

Bromodiphenhydramine hydrochloride Chemical Structure

CAS No. : 1808-12-4

Size Price Stock Quantity
5 mg USD 55 In-stock
10 mg USD 90 In-stock
25 mg USD 165 In-stock
50 mg USD 270 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Bromodiphenhydramine hydrochloride:

Bromodiphenhydramine hydrochloride Related Antibodies

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Description

Bromodiphenhydramine hydrochloride is a potent antihistamine with antimicrobial property. Bromodiphenhydramine hydrochloride inhibits a large number of Gram negative and Gram positive bacteria. Bromodiphenhydramine hydrochloride can be used for cutaneous allergies research[1][2][3].

In Vivo

Bromodiphenhydramine hydrochloride (1.5 and 3 μg/g, single) protects mice against a challenge with a virulent strain of Salmonella typhimurium, and also significantly reduces the multiplication of this organism in the liver, spleen and blood of the protected animals in comparison with the unprotected controls[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

370.71

Formula

C17H21BrClNO
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

BrC1=CC=C(C(C2=CC=CC=C2)OCCN(C)C)C=C1.[H]Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (337.19 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : 3.33 mg/mL (8.98 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6975 mL 13.4876 mL 26.9753 mL
5 mM 0.5395 mL 2.6975 mL 5.3951 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / DMSO 1 mM 2.6975 mL 13.4876 mL 26.9753 mL 67.4382 mL
5 mM 0.5395 mL 2.6975 mL 5.3951 mL 13.4876 mL
DMSO 10 mM 0.2698 mL 1.3488 mL 2.6975 mL 6.7438 mL
15 mM 0.1798 mL 0.8992 mL 1.7984 mL 4.4959 mL
20 mM 0.1349 mL 0.6744 mL 1.3488 mL 3.3719 mL
25 mM 0.1079 mL 0.5395 mL 1.0790 mL 2.6975 mL
30 mM 0.0899 mL 0.4496 mL 0.8992 mL 2.2479 mL
40 mM 0.0674 mL 0.3372 mL 0.6744 mL 1.6860 mL
50 mM 0.0540 mL 0.2698 mL 0.5395 mL 1.3488 mL
60 mM 0.0450 mL 0.2248 mL 0.4496 mL 1.1240 mL
80 mM 0.0337 mL 0.1686 mL 0.3372 mL 0.8430 mL
100 mM 0.0270 mL 0.1349 mL 0.2698 mL 0.6744 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Bromodiphenhydramine hydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Bromodiphenhydramine1808-12-4AmbodrylHistamine ReceptorBacterialcutaneous allergiesbacteriaSalmonella typhimuriumantihistamineInhibitorinhibitorinhibit

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