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  4. Bromonitromethane

Bromonitromethane is a halonitromethane that can be used in production of various protected α-bromo nitroalkane donors for use in Umpolung Amide Synthesis (UmAS).

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Bromonitromethane Chemical Structure

Bromonitromethane Chemical Structure

CAS No. : 563-70-2

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Bromonitromethane Related Antibodies

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Description

Bromonitromethane is a halonitromethane that can be used in production of various protected α-bromo nitroalkane donors for use in Umpolung Amide Synthesis (UmAS)[1][2].

Molecular Weight

139.94

Formula

CH2BrNO2
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

O=[N+](CBr)[O-]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (714.59 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 7.1459 mL 35.7296 mL 71.4592 mL
5 mM 1.4292 mL 7.1459 mL 14.2918 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 7.1459 mL 35.7296 mL 71.4592 mL 178.6480 mL
5 mM 1.4292 mL 7.1459 mL 14.2918 mL 35.7296 mL
10 mM 0.7146 mL 3.5730 mL 7.1459 mL 17.8648 mL
15 mM 0.4764 mL 2.3820 mL 4.7639 mL 11.9099 mL
20 mM 0.3573 mL 1.7865 mL 3.5730 mL 8.9324 mL
25 mM 0.2858 mL 1.4292 mL 2.8584 mL 7.1459 mL
30 mM 0.2382 mL 1.1910 mL 2.3820 mL 5.9549 mL
40 mM 0.1786 mL 0.8932 mL 1.7865 mL 4.4662 mL
50 mM 0.1429 mL 0.7146 mL 1.4292 mL 3.5730 mL
60 mM 0.1191 mL 0.5955 mL 1.1910 mL 2.9775 mL
80 mM 0.0893 mL 0.4466 mL 0.8932 mL 2.2331 mL
100 mM 0.0715 mL 0.3573 mL 0.7146 mL 1.7865 mL
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Bromonitromethane Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Bromonitromethane563-70-2OthersUmAScarcinogenichalonitromethaneα-bromonitroalkaneInhibitorinhibitorinhibit

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