1. Protein Tyrosine Kinase/RTK
  2. Tie
  3. BSF-466895

BSF-466895(A-422885.66) is a Tie2 inhibitor with an IC50 of 5 nM and it can also inhibit Tie1.

For research use only. We do not sell to patients.

BSF-466895 Chemical Structure

BSF-466895 Chemical Structure

CAS No. : 262442-90-0

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Description

BSF-466895(A-422885.66) is a Tie2 inhibitor with an IC50 of 5 nM and it can also inhibit Tie1[1][2].

IC50 & Target

Tie2

5 nM (IC50)

Molecular Weight

632.58

Formula

C29H32Cl2FN7O2S

CAS No.
SMILES

O=S(C1=CC=CC(Cl)=C1Cl)(NC2=CC=C(C3=CN([C@H]4CC[C@H](N5CCN(C)CC5)CC4)C6=NC=NC(N)=C63)C=C2F)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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BSF-466895 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
BSF-466895
Cat. No.:
HY-15973
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