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c-ABL-IN-1 is a novel selective c-Abl inhibitor that prevents neurodegeneration in parkinson’s disease.

For research use only. We do not sell to patients.

c-ABL-IN-1 Chemical Structure

c-ABL-IN-1 Chemical Structure

CAS No. : 2304918-82-7

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c-ABL-IN-1 Related Antibodies

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Description

c-ABL-IN-1 is a novel selective c-Abl inhibitor that prevents neurodegeneration in parkinson’s disease.

Cellular Effect
Cell Line Type Value Description References
SH-SY5Y GI50
39.96 μM
Compound: 5
Antiproliferative activity against human SH-SY5Y cells assessed as inhibition of cell survival incubated for 48 hrs by MTS assay
Antiproliferative activity against human SH-SY5Y cells assessed as inhibition of cell survival incubated for 48 hrs by MTS assay
[PMID: 34583507]
Molecular Weight

400.30

Formula

C17H16Cl2FN3OS
CAS No.
SMILES

O=C([C@H]1[C@@H](F)C1)NC2=NC3=CC=C(C4=C(C)C=CN=C4)C=C3S2.[H]Cl.[H]Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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c-ABL-IN-1 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

c-ABL-IN-12304918-82-7OthersInhibitorinhibitorinhibit

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