2. Protein Tyrosine Kinase/RTK
  3. c-Kit
  4. c-Kit-IN-7

c-Kit-IN-7 (Compound 104) is a potent inhibitor of c-Kit, with IC50 values of ≤10 nM. c-Kit-IN-7 inhibits the cell proliferation in GIST430 and BaF3 mutants, with IC50 values of ≤100 nM. c-Kit-IN-7 plays an important role in cancer driven by c-KIT kinase mutations research.

For research use only. We do not sell to patients.

c-Kit-IN-7 Chemical Structure

c-Kit-IN-7 Chemical Structure

CAS No. : 2941026-35-1

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c-Kit-IN-7 Related Antibodies

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Description

c-Kit-IN-7 (Compound 104) is a potent inhibitor of c-Kit, with IC50 values of ≤10 nM. c-Kit-IN-7 inhibits the cell proliferation in GIST430 and BaF3 mutants, with IC50 values of ≤100 nM. c-Kit-IN-7 plays an important role in cancer driven by c-KIT kinase mutations research[1].

Molecular Weight

521.59

Formula

C27H32FN7O3
CAS No.
SMILES

CC(C#N)(CCNC(NC1=CC=C(C=C1)NC2=NC=NC3=CC(OCCN4CCOCC4)=CC(F)=C32)=O)C
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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c-Kit-IN-7 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

c-Kit-IN-72941026-35-1c-KitSCFRCD117GIST430 mutantBaF3 mutantInhibitorinhibitorinhibit

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