2. Protein Tyrosine Kinase/RTK
  3. c-Kit
  4. c-Kit-IN-8

c-Kit-IN-8 (Compound 53) is an inhibitor for c-Kit kinase, that inhibits uKIT kinase with an IC50 > 1 μM. c-Kit-IN-8 inhibits the proliferation of cancer cell GIST430 and BaF3 wildtype and mutants with IC50 > 0.1 μM.

For research use only. We do not sell to patients.

c-Kit-IN-8 Chemical Structure

c-Kit-IN-8 Chemical Structure

CAS No. : 2941024-89-9

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c-Kit-IN-8 Related Antibodies

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Description

c-Kit-IN-8 (Compound 53) is an inhibitor for c-Kit kinase, that inhibits uKIT kinase with an IC50 > 1 μM. c-Kit-IN-8 inhibits the proliferation of cancer cell GIST430 and BaF3 wildtype and mutants with IC50 > 0.1 μM[1].

Molecular Weight

467.49

Formula

C24H26FN5O4
CAS No.
SMILES

COCCOC1=CC(F)=C2C(N=CN=C2NC3=CC=C(C=C3)NC(CCN4CCCC4=O)=O)=C1
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Purity & Documentation
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c-Kit-IN-8 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

c-Kit-IN-82941024-89-9c-KitSCFRCD117GIST430BaF3Inhibitorinhibitorinhibit

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