C18:1-Ceramide-¹³C₁₈

Cat. No.: HY-141578S Purity: 97.0%: FAQs
Data Sheet SDS COA Handling Instructions Technical Support

C18:1-Ceramide-¹³C₁₈ is a ¹³C-labeled C16-Ceramide[1].

For research use only. We do not sell to patients.

C18:1-Ceramide-<sup>13</sup>C<sub>18</sub> Chemical Structure

C18:1-Ceramide-¹³C₁₈ Chemical Structure

Size	Stock	Quantity
1 mg	In-stock	Estimated Time of Arrival: December 31
5 mg	Get quote
10 mg	Get quote

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Other Forms of C18:1-Ceramide-¹³C₁₈:

C18:1-Ceramide Get quote

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Biological Activity
Purity & Documentation
References
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Description

C18:1-Ceramide-¹³C₁₈ is a ¹³C-labeled C16-Ceramide[1].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[75].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

581.81

Formula

C₁₈¹³C₁₈H₆₉NO₃

Unlabeled CAS

5966-28-9

Appearance

Solid

Color

White to off-white

SMILES

[13CH3][13CH2][13CH2][13CH2][13CH2][13CH2][13CH2][13CH2]/[13CH]=[13CH]\[13CH2][13CH2][13CH2][13CH2][13CH2][13CH2][13CH2][13C](N[C@H]([C@@H](/C=C/CCCCCCCCCCCCC)O)CO)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

DMF : 100 mg/mL (171.88 mM; Need ultrasonic and warming)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.7188 mL	8.5939 mL	17.1877 mL
5 mM	0.3438 mL	1.7188 mL	3.4375 mL
10 mM	0.1719 mL	0.8594 mL	1.7188 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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Concentration _(final)

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In Vivo Dissolution Calculator

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 97.0%

Select Batch:

Data Sheet (267 KB) SDS (251 KB)

COA (240 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMF	1 mM	1.7188 mL	8.5939 mL	17.1877 mL	42.9694 mL
	5 mM	0.3438 mL	1.7188 mL	3.4375 mL	8.5939 mL
	10 mM	0.1719 mL	0.8594 mL	1.7188 mL	4.2969 mL
	15 mM	0.1146 mL	0.5729 mL	1.1458 mL	2.8646 mL
	20 mM	0.0859 mL	0.4297 mL	0.8594 mL	2.1485 mL
	25 mM	0.0688 mL	0.3438 mL	0.6875 mL	1.7188 mL
	30 mM	0.0573 mL	0.2865 mL	0.5729 mL	1.4323 mL
	40 mM	0.0430 mL	0.2148 mL	0.4297 mL	1.0742 mL
	50 mM	0.0344 mL	0.1719 mL	0.3438 mL	0.8594 mL
	60 mM	0.0286 mL	0.1432 mL	0.2865 mL	0.7162 mL
	80 mM	0.0215 mL	0.1074 mL	0.2148 mL	0.5371 mL
	100 mM	0.0172 mL	0.0859 mL	0.1719 mL	0.4297 mL