C22 Phytoceramide-d₃ (t18:0/22:0) 

C22 Phytoceramide-d3 (t18:0/22:0) is a deuterated labeled C22 Phytoceramide (t18:0/22:0)^[1]. C22 Phytoceramide is a sphingolipid that has been found in Moro blood orange (C. sinensis) peels. It has also been found in primary human astrocytes.

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

643.09

C₄₀H₇₈D₃NO₄

2011762-87-9

164576-03-8

CCCCCCCCCCCCCC[C@@H](O)[C@@H](O)[C@H](CO)NC(CCCCCCCCCCCCCCCCCCCCC([2H])([2H])[2H])=O

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  [Content Brief]

  [2]. Valsecchi, et al. Ceramides as possible nutraceutical compounds: Characterization of the ceramides of the Moro blood orange (Citrus sinensis). J. Agric. Food Chem. 60(40), 10103-10110 (2012).