C24:1 1-Deoxyceramide (m18:1/24:1(15Z)) (Synonyms: C24:1(15Z) 1-Deoxyceramide; C24:1 Ceramide (m18:1/24:1(15Z)); Cer(m18:1/24:1(15Z)))

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C24:1 1-Deoxyceramide (m18:1/24:1(15Z)) (C24:1(15Z) 1-Deoxyceramide) is a lipid molecule, which is composed of a long-chain fatty acid (24:1) and a 1-deoxysphingoid backbone. Deoxyceramide accumulates under the conditions of obesity and type 2 diabetes (T2D). Deoxyceramide is unable to be further metabolized to more complex sphingolipid, and is toxic when accumulates in the body. Deoxyceramide increases in differentiated adipocytes in vitro.

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C24:1 1-Deoxyceramide (m18:1/24:1(15Z)) Chemical Structure

CAS No. : 1246298-58-7

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Description	C24:1 1-Deoxyceramide (m18:1/24:1(15Z)) (C24:1(15Z) 1-Deoxyceramide) is a lipid molecule, which is composed of a long-chain fatty acid (24:1) and a 1-deoxysphingoid backbone. Deoxyceramide accumulates under the conditions of obesity and type 2 diabetes (T2D). Deoxyceramide is unable to be further metabolized to more complex sphingolipid, and is toxic when accumulates in the body. Deoxyceramide increases in differentiated adipocytes in vitro^[1].
Molecular Weight	632.10
Formula	C₄₂H₈₁NO₂
CAS No.	1246298-58-7
SMILES	CCCCCCCCCCCCC/C=C/[C@@H](O)[C@H](C)NC(CCCCCCCCCCCCC/C=C\CCCCCCCC)=O
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (260 KB) Handling Instructions (2659 KB)
References	[1]. Hannich JT, et al., Ether lipids, sphingolipids and toxic 1-deoxyceramides as hallmarks for lean and obese type 2 diabetic patients. Acta Physiol (Oxf). 2021 May;232(1):e13610. [Content Brief]

C24:1 1-Deoxyceramide (m18:1/24:1(15Z)) Related Classifications

Metabolic Disease

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

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C24:1 1-Deoxyceramide (m18:1/24:1(15Z))1246298-58-7C24:1(15Z) 1-Deoxyceramide C24:1 Ceramide (m18:1/24:1(15Z)) Cer(m18:1/24:1(15Z))Endogenous MetaboliteT2Dtype 2 diabeteobesityadipocyteInhibitorinhibitorinhibit

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C24:1 1-Deoxyceramide (m18:1/24:1(15Z)) (Synonyms: C24:1(15Z) 1-Deoxyceramide; C24:1 Ceramide (m18:1/24:1(15Z)); Cer(m18:1/24:1(15Z)))

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