2. Anti-infection
  3. Bacterial
  4. C450-0730

C450-0730 is an antagonist targeting the AHL membrane-bound sensor kinase and is an antagonist of the nine-transmembrane protein LuxN of Vibrio harveyi . C450-0730 competitively binds to the LuxN AI-1 binding site and specifically antagonizes the LuxN/AI-1 quorum sensing signal in Vibrio harveyi. The inhibitory activity of C450-0730 against LuxNI209F was not significant.

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C450-0730 Chemical Structure

C450-0730 Chemical Structure

CAS No. : 1036730-46-7

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C450-0730 Related Antibodies

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Description

C450-0730 is an antagonist targeting the AHL membrane-bound sensor kinase and is an antagonist of the nine-transmembrane protein LuxN of Vibrio harveyi . C450-0730 competitively binds to the LuxN AI-1 binding site and specifically antagonizes the LuxN/AI-1 quorum sensing signal in Vibrio harveyi. The inhibitory activity of C450-0730 against LuxNI209F was not significant[1].

IC50 & Target

LuxN/AI-1[1]
Molecular Weight

478.00

Formula

C23H28ClN3O4S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CC(C)CC(NS(=O)(C1=CC2=C(N(C(C)=O)CC2)C=C1)=O)C(NCC3=CC=C(Cl)C=C3)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
References
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C450-0730 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

C450-07301036730-46-7BacterialMembrane-bound sensorVibrio harveyiquorum sensingInhibitorinhibitorinhibit

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