1. Immunology/Inflammation
  2. Complement System
  3. C5aR2 agonist P32 acetate

C5aR2 agonist P32 (Ac-RHYPYWR-OH) acetate is a C5aR2-selective agonist. C5aR2 agonist P32 acetate has been shown to elicit multiple immunomodulatory activities, both by down-regulating the C5aR1-mediated cell signalling, and acting in a C5aR1-independent fashion, in vitro and in vivo.

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C5aR2 agonist P32 acetate Chemical Structure

C5aR2 agonist P32 acetate Chemical Structure

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Description

C5aR2 agonist P32 (Ac-RHYPYWR-OH) acetate is a C5aR2-selective agonist. C5aR2 agonist P32 acetate has been shown to elicit multiple immunomodulatory activities, both by down-regulating the C5aR1-mediated cell signalling, and acting in a C5aR1-independent fashion, in vitro and in vivo[1].

Molecular Weight

1119.23 (free base)

Formula

C54H70N16O11.xC2H4O2

Sequence

Ac-Arg-His-Tyr-Pro-Tyr-Trp-Arg

Sequence Shortening

Ac-RHYPYWR

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
C5aR2 agonist P32 acetate
Cat. No.:
HY-P10639A
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