2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. Calcium Channel
  4. Calcium Channel antagonist 3

Calcium Channel antagonist 3 

Cat. No.: HY-156664 Purity: ≥98.0%
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Calcium Channel antagonist 3 (compound 397) is an inhibitor of voltage-gated calcium channels with an IC50 value of 5-20μM.

For research use only. We do not sell to patients.

Calcium Channel antagonist 3 Chemical Structure

Calcium Channel antagonist 3 Chemical Structure

CAS No. : 687573-14-4

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Based on 1 publication(s) in Google Scholar

Calcium Channel antagonist 3 Related Antibodies

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N-type calcium channel L-type calcium channel P/Q-type calcium channel T-type calcium channel Calcium Channel

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Description

Calcium Channel antagonist 3 (compound 397) is an inhibitor of voltage-gated calcium channels with an IC50 value of 5-20μM[1].

Molecular Weight

426.53

Formula

C23H26N2O4S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(C1=C(C)C2=C(C=CC(S(=O)(N3CCCC(C3)C)=O)=C2)O1)NCC4=CC=CC=C4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (117.23 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3445 mL 11.7225 mL 23.4450 mL
5 mM 0.4689 mL 2.3445 mL 4.6890 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.3445 mL 11.7225 mL 23.4450 mL 58.6125 mL
5 mM 0.4689 mL 2.3445 mL 4.6890 mL 11.7225 mL
10 mM 0.2345 mL 1.1723 mL 2.3445 mL 5.8613 mL
15 mM 0.1563 mL 0.7815 mL 1.5630 mL 3.9075 mL
20 mM 0.1172 mL 0.5861 mL 1.1723 mL 2.9306 mL
25 mM 0.0938 mL 0.4689 mL 0.9378 mL 2.3445 mL
30 mM 0.0782 mL 0.3908 mL 0.7815 mL 1.9538 mL
40 mM 0.0586 mL 0.2931 mL 0.5861 mL 1.4653 mL
50 mM 0.0469 mL 0.2345 mL 0.4689 mL 1.1723 mL
60 mM 0.0391 mL 0.1954 mL 0.3908 mL 0.9769 mL
80 mM 0.0293 mL 0.1465 mL 0.2931 mL 0.7327 mL
100 mM 0.0234 mL 0.1172 mL 0.2345 mL 0.5861 mL
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Calcium Channel antagonist 3 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Calcium Channel antagonist 3687573-14-4Calcium Channel antagonist3Calcium Channel antagonist-3Calcium ChannelCa2+ channelsCa channelsInhibitorinhibitorinhibit

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