2. Cell Cycle/DNA Damage
  3. Antifolate
  4. Calcium N5-methyltetrahydrofolate

Calcium N5-methyltetrahydrofolate  (Synonyms: NSC173328; 5-Methyl THF calcium)

Cat. No.: HY-17557 Purity: 98.56%
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Calcium N5-methyltetrahydrofolate(NSC173328) is the calcium salt of levomefolic acid, which has been proposed for treatment of cardiovascular disease and advanced cancers such as breast and colorectal cancers.

For research use only. We do not sell to patients.

Calcium N5-methyltetrahydrofolate Chemical Structure

Calcium N5-methyltetrahydrofolate Chemical Structure

CAS No. : 26560-38-3

Size Price Stock Quantity
1 mg USD 95 In-stock
5 mg USD 218 In-stock
10 mg USD 350 In-stock
25 mg USD 665 In-stock
50 mg USD 1030 In-stock
100 mg USD 1597 In-stock
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Based on 5 publication(s) in Google Scholar

Other Forms of Calcium N5-methyltetrahydrofolate:

Calcium N5-methyltetrahydrofolate Related Antibodies

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Description

Calcium N5-methyltetrahydrofolate(NSC173328) is the calcium salt of levomefolic acid, which has been proposed for treatment of cardiovascular disease and advanced cancers such as breast and colorectal cancers. IC50 value: Target:

Molecular Weight

497.52

Formula

C20H23CaN7O6
CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

O=C([O-])CC[C@@H](C([O-])=O)NC(C1=CC=C(NCC2N(C)C3=C(N=C(N)NC3=O)NC2)C=C1)=O.[Ca+2]
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Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 20 mg/mL (40.20 mM; ultrasonic and adjust pH to 2 with 1 M HCL)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.0100 mL 10.0498 mL 20.0997 mL
5 mM 0.4020 mL 2.0100 mL 4.0199 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 2.0100 mL 10.0498 mL 20.0997 mL 50.2492 mL
5 mM 0.4020 mL 2.0100 mL 4.0199 mL 10.0498 mL
10 mM 0.2010 mL 1.0050 mL 2.0100 mL 5.0249 mL
15 mM 0.1340 mL 0.6700 mL 1.3400 mL 3.3499 mL
20 mM 0.1005 mL 0.5025 mL 1.0050 mL 2.5125 mL
25 mM 0.0804 mL 0.4020 mL 0.8040 mL 2.0100 mL
30 mM 0.0670 mL 0.3350 mL 0.6700 mL 1.6750 mL
40 mM 0.0502 mL 0.2512 mL 0.5025 mL 1.2562 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Calcium N5-methyltetrahydrofolate Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Calcium N5-methyltetrahydrofolate26560-38-3NSC1733285-Methyl THFNSC 173328NSC-173328AntifolateInhibitorinhibitorinhibit

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