Canertinib dihydrochloride (Standard) (Synonyms: CI-1033 dihydrochloride (Standard); PD-183805 dihydrochloride (Standard))

Cat. No.: HY-10367AR Purity: ≥98%: FAQs
Handling Instructions Technical Support

Canertinib (dihydrochloride) (Standard) is the analytical standard of Canertinib (dihydrochloride). This product is intended for research and analytical applications. Canertinib dihydrochloride (CI-1033 dihydrochloride) is a potent and irreversible EGFR inhibitor; inhibits cellular EGFR and ErbB2 autophosphorylation with IC50s of 7.4 and 9 nM. Canertinib dihydrochloride is active against vaccinia virus respiratory infection in mice[1][2][3][4].

For research use only. We do not sell to patients.

Canertinib dihydrochloride (Standard) Chemical Structure

CAS No. : 289499-45-2

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Description	Canertinib (dihydrochloride) (Standard) is the analytical standard of Canertinib (dihydrochloride). This product is intended for research and analytical applications. Canertinib dihydrochloride (CI-1033 dihydrochloride) is a potent and irreversible EGFR inhibitor; inhibits cellular EGFR and ErbB2 autophosphorylation with IC50s of 7.4 and 9 nM. Canertinib dihydrochloride is active against vaccinia virus respiratory infection in mice[1][2][3][4].
Molecular Weight	558.86
Formula	C₂₄H₂₇Cl₃FN₅O₃
CAS No.	289499-45-2
SMILES	C=CC(NC1=CC2=C(N=CN=C2C=C1OCCCN3CCOCC3)NC4=CC=C(C(Cl)=C4)F)=O.[H]Cl.[H]Cl
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Handling Instructions (2659 KB)

Canertinib dihydrochloride (Standard) Related Classifications

Infection Cancer

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Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

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Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Canertinib dihydrochloride (Standard)289499-45-2CI-1033 dihydrochloride (Standard)PD-183805 dihydrochloride (Standard)EGFROrthopoxvirusEpidermal growth factor receptorErbB-1HER1Inhibitorinhibitorinhibit

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Canertinib dihydrochloride (Standard) (Synonyms: CI-1033 dihydrochloride (Standard); PD-183805 dihydrochloride (Standard))

Product Information

Purity & Documentation

Customer Review

Canertinib dihydrochloride (Standard) Related Classifications

Molarity Calculator

Dilution Calculator