2. Metabolic Enzyme/Protease
  3. Carbonic Anhydrase
  4. Carbonic anhydrase inhibitor 10

Carbonic anhydrase inhibitor 10 is a potent hCA IX inhibitor with a Ki value of 6.2 nM. Carbonic anhydrase inhibitor 10 exhibits anti-proliferative activity against MCF-7 cancer cell line with an IC50 of 11.9 μM. Carbonic anhydrase inhibitor 10 can be used for cancer research.

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Carbonic anhydrase inhibitor 10 Chemical Structure

Carbonic anhydrase inhibitor 10 Chemical Structure

CAS No. : 2883453-30-1

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Carbonic anhydrase inhibitor 10 Related Antibodies

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CA CA I CA Ⅱ CA Ⅸ CA XII

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Description

Carbonic anhydrase inhibitor 10 is a potent hCA IX inhibitor with a Ki value of 6.2 nM. Carbonic anhydrase inhibitor 10 exhibits anti-proliferative activity against MCF-7 cancer cell line with an IC50 of 11.9 μM. Carbonic anhydrase inhibitor 10 can be used for cancer research[1].

IC50 & Target

CA Ⅸ

 

Cellular Effect
Cell Line Type Value Description References
MCF7 IC50
11.92 μM
Compound: 6c
Antiproliferative activity against human MCF7 cells assessed as cell growth inhibition measured for 72 hrs by MTT assay
Antiproliferative activity against human MCF7 cells assessed as cell growth inhibition measured for 72 hrs by MTT assay
[PMID: 34871842]
Molecular Weight

335.38

Formula

C14H17N5O3S
CAS No.
SMILES

CC1=NC(C)=C(N=C1NC(NC2=CC=C(C=C2)S(N)(=O)=O)=O)C
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Carbonic anhydrase inhibitor 10 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Carbonic anhydrase inhibitor 102883453-30-1Carbonic anhydrase inhibitor10Carbonic anhydrase inhibitor-10Carbonic AnhydraseCarbonate dehydrataseMCF-7canceranticancerpro-apoptoticInhibitorinhibitorinhibit

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