2. Anti-infection
  3. Parasite
  4. Carbonic anhydrase inhibitor 27

Carbonic anhydrase inhibitor 27 (compund 5g) is an antitrypanosomal agent that reduces parasites in the bloodstream and improves survival of infected mice.

For research use only. We do not sell to patients.

Carbonic anhydrase inhibitor 27 Chemical Structure

Carbonic anhydrase inhibitor 27 Chemical Structure

CAS No. : 167098-81-9

Size Stock
50 mg   Get quote  
100 mg   Get quote  
250 mg   Get quote  
Synthetic products have potential research and development risk.

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Carbonic anhydrase inhibitor 27 Related Antibodies

Top Publications Citing Use of Products

View All Parasite Isoform Specific Products:

View All Isoforms
Amebae Coccidia Leishmania Mite Plasmodium Toxoplasma Trypanosoma Schistosome

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Carbonic anhydrase inhibitor 27 (compund 5g) is an antitrypanosomal agent that reduces parasites in the bloodstream and improves survival of infected mice[1].

Cellular Effect
Cell Line Type Value Description References
Peritoneal macrophage cell CC50
64 μM
Compound: 5g
Cytotoxicity against BALB/c mouse peritoneal macrophages after 48 hrs by MTT/LDH assay
Cytotoxicity against BALB/c mouse peritoneal macrophages after 48 hrs by MTT/LDH assay
[PMID: 24299463]
Peritoneal macrophage cell CC50
92 μM
Compound: 5g
Cytotoxicity against BALB/c mouse peritoneal macrophages after 24 hrs by MTT/LDH assay
Cytotoxicity against BALB/c mouse peritoneal macrophages after 24 hrs by MTT/LDH assay
[PMID: 24299463]
THP-1 IC50
< 1 μM
Compound: 5g
Antitrypanosomal activity against Trypanosoma cruzi Y infected in human THP1 cells assessed as reduction of parasite burden after 48 hrs by Giemsa staining-based Neubauer chamber counting analysis
Antitrypanosomal activity against Trypanosoma cruzi Y infected in human THP1 cells assessed as reduction of parasite burden after 48 hrs by Giemsa staining-based Neubauer chamber counting analysis
[PMID: 24299463]
Molecular Weight

312.32

Formula

C17H16N2O4
CAS No.
SMILES

O=C(C1ON=C(C1)C2=CC=C(OCC3=CC=CC=C3)C=C2)NO
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

Carbonic anhydrase inhibitor 27 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Carbonic anhydrase inhibitor 27167098-81-9Carbonic anhydrase inhibitor27Carbonic anhydrase inhibitor-27ParasiteInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Carbonic anhydrase inhibitor 27
Cat. No.:
HY-12610
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

SAFETY DATA SHEET (SDS)

English - EN (0 KB) Français - FR (0 KB) Deutsch - DE (0 KB) Norwegian - NO (0 KB) Español - ES (0 KB) Swedish - SV (0 KB)

Request for HNMR Report

We have received your request and will respond to you as soon as possible.